Across TCGA cell cohorts, FAM72D mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM72D-associated genes across cancer lineages are DAZ2, FAM170B, and TOPAZ1. Each is linked with FAM72D in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM72D-to-partner and partner-to-FAM72D results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM72D→partner) and Y-score (partner→FAM72D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	DAZ2 →	+0.336	+5.415	<.001	.004	3	2
LUNG_SCLC	FAM170B →	+0.049	+4.044	<.001	.009	3	1
LUNG_SCLC	TOPAZ1 →	+0.031	+4.523	<.001	.003	3	1
LUNG_SCLC	OR4N2 →	+0.035	+4.269	<.001	.005	3	1
LUNG_SCLC	GIMD1 →	+0.030	+4.817	<.001	.001	3	1
LARGE_INTESTINE	DAZ4 →	+0.326	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

FAM72D survival (RNA) · tumor vs normal (RNA) · all FAM72D data types