Across TCGA pan-cancer cohorts, FAM72D RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated FAM72D data layer.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher FAM72D RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM72D expression acts as an unfavorable survival marker, although some lineages such as GBM and THYM show a favorable association.
ACC, KIRC, and KIRP are the cancer types where FAM72D RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.