FAM72C

Across TCGA pan-cancer cohorts, FAM72C RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FAM72C data layer compared with 1 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher FAM72C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM72C expression acts as an unfavorable survival marker, although some lineages such as LUSC and THYM show a favorable association.

KIRC, KIRP, and ACC are the cancer types where FAM72C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.546	0.711	<.001	152	view →
KIRP	OS	Tertile	All	0.534	0.757	<.001	131	view →
ACC	DFS	Median	All	0.233	0.698	<.001	117	view →
LUAD	OS	Median	All	0.601	0.768	<.001	91	view →
LIHC	OS	Median	All	0.594	0.771	<.001	85	view →
MESO	OS	Median	All	0.410	0.672	<.001	75	view →
UVM	DFS	Tertile	All	0.317	0.677	<.001	64	view →
COAD	OS	Quartile	All	0.776	0.907	.001	52	view →
KICH	DFS	Tertile	III,IV	0.129	0.893	<.001	50	view →
LGG	DFS	Median	All	0.664	0.802	<.001	47	view →
SARC	DFS	Quartile	All	0.530	0.700	.006	19	view →
UCEC	DFS	Quartile	All	0.850	0.941	.001	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

FAM72C–KIRC (OS)

Open the KIRC breakdown →