Across TCGA patient cohorts, FAM72A mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible FAM72A-associated genes across cancer lineages are CSTP2, FAM27B, and ZNF519P3. Each is linked with FAM72A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM72A-to-partner and partner-to-FAM72A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM72A→partner) and Y-score (partner→FAM72A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CSTP2 →	+0.107	+5.436	<.001	.005	3	1
SKCM	FAM27B →	+0.442	+5.867	<.001	.003	3	1
SKCM	ZNF519P3 →	+0.053	+8.228	<.001	<.001	3	1
SKCM	MIR4296 →	+0.445	+4.979	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

FAM72A survival (RNA) · tumor vs normal (RNA) · all FAM72A data types