FAM71F1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FAM71F1 mutation is significantly associated with the RNA expression of many other genes, with 791 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71F1-associated genes across cancer lineages are LINC00351, MTND4P28, and RNU6-484P. Each is linked with FAM71F1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71F1-to-partner and partner-to-FAM71F1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00351 grouped by FAM71F1-low versus FAM71F1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71F1→partner) and Y-score (partner→FAM71F1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC00351 →+0.266+5.201<.001.00732
BLCAMTND4P28 →+0.062+4.814<.001.00332
SKCMRNU6-484P →+0.368+3.024.008.00532
UCECPEAK3 →+0.221+3.354.003.00532
UCECRNU2-47P →+0.077+3.973<.001.00632
LUSCRNU6-706P →+0.227+4.467<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 791 associations by consensus.

LINC00351 by FAM71F1 expression — CESC

Box plot of LINC00351 in FAM71F1-low vs FAM71F1-high samples in CESC.

Explore this box plot interactively →

Exploration