FAM71D

Across TCGA patient cohorts, FAM71D mutation is significantly associated with the RNA expression of many other genes, with 2,626 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71D-associated genes across cancer lineages are MTND2P25, RN7SL654P, and RNU6ATAC14P. Each is linked with FAM71D in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM71D-to-partner and partner-to-FAM71D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND2P25 grouped by FAM71D-low versus FAM71D-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71D→partner) and Y-score (partner→FAM71D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MTND2P25 →	+0.099	+7.954	<.001	.008	3	3
UCEC	RN7SL654P →	+0.076	+2.261	.004	.004	3	3
SKCM	RNU6ATAC14P →	+0.407	+2.502	<.001	<.001	3	2
SKCM	BCL2L2-PABPN1 →	+0.383	+2.144	<.001	.009	3	2
UCEC	HNRNPA1P71 →	+0.154	+1.883	<.001	<.001	3	2
HNSC	LINC02379 →	+0.189	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,626 associations by consensus.

MTND2P25 by FAM71D expression — HNSC

Explore this box plot interactively →