FAM71D

Across TCGA pan-cancer cohorts, FAM71D RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated FAM71D data layer compared with 4 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher FAM71D RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM71D expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

KICH, BLCA, and LIHC are the cancer types where FAM71D RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Quartile	All	0.683	1.000	.001	34	view →
BLCA	OS	Quartile	II,III,IV	0.604	0.477	.024	31	view →
LIHC	OS	Median	All	0.427	0.718	<.001	28	view →
CESC	OS	Tertile	All	0.766	0.414	.002	28	view →
KIRC	DFS	Median	II,III,IV	0.401	0.603	.004	27	view →
SKCM	OS	Median	III,IV	0.803	0.614	<.001	27	view →
LGG	DFS	Quartile	All	0.613	0.810	<.001	26	view →
COAD	OS	Quartile	IV	0.362	0.768	.004	26	view →
READ	OS	Median	III,IV	0.724	0.265	<.001	23	view →
KIRP	DFS	Quartile	All	0.327	0.807	.020	16	view →
ACC	OS	Median	IV	0.307	0.778	.019	15	view →
LUSC	OS	Tertile	II,III,IV	0.242	0.515	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

FAM71D–KICH (OS)

Open the KICH breakdown →