FAM71C

Across TCGA patient cohorts, FAM71C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,782 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM71C-associated GO terms across cancer lineages are Cytokinesis, Protein localization to cytoskeleton, and Obsolete histone H3-K4 methylation. Each is linked with FAM71C in more than 19 cancer types. Because this analysis shows association rather than direction, both FAM71C-to-partner and partner-to-FAM71C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytokinesis grouped by FAM71C-low versus FAM71C-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71C→partner) and Y-score (partner→FAM71C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cytokinesis →	+0.064	+0.142	<.001	.001	3	20
STAD	Protein localization to cytoskeleton →	+0.072	+0.109	<.001	<.001	3	20
STAD	Obsolete histone H3-K4 methylation →	+0.077	+0.102	<.001	<.001	3	19
STAD	DNA-templated transcription elongation →	+0.076	+0.114	<.001	<.001	3	19
STAD	Microtubule nucleation →	+0.074	+0.112	<.001	<.001	3	19
ESCA	Regulation of microtubule cytoskeleton organization →	+0.067	+0.150	<.001	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,782 associations by consensus.

Cytokinesis by FAM71C expression — ESCA

Explore this box plot interactively →