FAM71C

Across TCGA patient cohorts, FAM71C mutation is significantly associated with the RNA expression of many other genes, with 226 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71C-associated genes across cancer lineages are RNU7-26P, RNA5SP443, and C19orf54. Each is linked with FAM71C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71C-to-partner and partner-to-FAM71C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-26P grouped by FAM71C-low versus FAM71C-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71C→partner) and Y-score (partner→FAM71C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU7-26P →	+0.672	+3.685	<.001	.001	3	2
BLCA	RNA5SP443 →	+0.511	+5.329	<.001	.006	3	2
SKCM	C19orf54 →	+0.503	+3.328	.002	.005	3	2
SKCM	RN7SL493P →	+0.087	+3.503	<.001	<.001	3	2
LUSC	RPS10P21 →	+0.167	+3.662	<.001	.001	3	2
UCEC	RNU6-741P →	+0.463	+4.245	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 226 associations by consensus.

RNU7-26P by FAM71C expression — LUAD

Explore this box plot interactively →