FAM71C

Across TCGA patient cohorts, FAM71C mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM71C-associated genes across cancer lineages are GMP, MPP, and Osteoblast. Each is linked with FAM71C in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM71C-to-partner and partner-to-FAM71C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by FAM71C-low versus FAM71C-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71C→partner) and Y-score (partner→FAM71C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.028	+2.264	.018	.043	3	3
COAD	MPP →	+0.016	+2.140	.021	.028	3	2
LUAD	Osteoblast →	+0.037	+2.324	<.001	.038	3	1
BLCA	naive B-cells →	+0.023	+4.173	.009	.027	3	1
UCEC	cDC →	+0.222	+2.815	<.001	.036	3	1
UCEC	DC →	+0.026	+3.234	.018	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

GMP by FAM71C expression — LUSC

Explore this box plot interactively →