FAM71C

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM71C mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM71C-associated genes across cancer lineages are IQCF6. Each is linked with FAM71C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71C-to-partner and partner-to-FAM71C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF6 grouped by FAM71C-low versus FAM71C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71C→partner) and Y-score (partner→FAM71C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEIQCF6 →+0.311+4.467<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

IQCF6 by FAM71C expression — LARGE_INTESTINE

Box plot of IQCF6 in FAM71C-low vs FAM71C-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration