FAM71A

Across TCGA patient cohorts, FAM71A protein abundance is significantly associated with the RNA expression of many other genes, with 119 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM71A-associated genes across cancer lineages are SEZ6L, THOC5, and KCTD17. Each is linked with FAM71A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM71A-to-partner and partner-to-FAM71A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM71A versus SEZ6L in GBM, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71A→partner) and Y-score (partner→FAM71A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEZ6L →	-2.253	-0.662	.004	.006	3	1
GBM	THOC5 →	-0.602	-0.731	.003	.001	3	1
GBM	KCTD17 →	-0.764	-0.876	.002	.008	3	1
GBM	SGK2 →	+0.916	+0.647	.004	.008	3	1
GBM	EEF1A2 →	-1.923	-0.719	<.001	.002	3	1
GBM	JADE3 →	-1.373	-0.884	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 119 associations by consensus.

FAM71A vs SEZ6L — GBM

Explore this scatter interactively →