FAM71A

Across TCGA pan-cancer cohorts, FAM71A RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated FAM71A data layer compared with 9 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in thymoma (THYM), where higher FAM71A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM71A expression acts as an unfavorable survival marker.

THYM, COAD, and ESCA are the cancer types where FAM71A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	All	0.778	0.976	<.001	69	view →
COAD	OS	Tertile	III,IV	0.153	0.581	.002	54	view →
ESCA	DFS	Tertile	All	0.271	0.441	.006	52	view →
LGG	DFS	Tertile	All	0.613	0.767	<.001	45	view →
KIRC	OS	Quartile	II,III,IV	0.291	0.564	.002	42	view →
LUSC	OS	Tertile	All	0.363	0.546	.011	33	view →
LUAD	OS	Tertile	II,III,IV	0.588	0.729	.015	12	view →
LAML	DFS	Tertile	All	0.262	0.461	.019	8	view →
THCA	OS	Tertile	IV	0.444	0.871	.001	6	view →
HNSC	OS	Tertile	IV	0.597	0.746	.035	3	view →
LIHC	OS	Tertile	All	0.482	0.784	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

FAM71A–THYM (OS)

Open the THYM breakdown →