FAM71A

Across TCGA cell cohorts, FAM71A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,427 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM71A-associated GO terms across cancer lineages are Regulation of tumor necrosis factor-mediated signaling pathway, Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors, and Response to corticosterone. Each is linked with FAM71A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM71A-to-partner and partner-to-FAM71A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor-mediated signaling pathway grouped by FAM71A-low versus FAM71A-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM71A→partner) and Y-score (partner→FAM71A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.107	+0.115	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors →	+0.359	+0.053	.003	.001	3	4
LUNG_NSCLC_LUAD	Response to corticosterone →	+0.180	+0.114	<.001	.006	3	4
BLOOD_Leukemia	Demethylation →	-0.054	-0.020	.002	.009	3	4
BLOOD_Lymphoma	Regulation of cytokine-mediated signaling pathway →	+0.072	+0.097	<.001	<.001	3	4
BLOOD_Lymphoma	Intracellular receptor signaling pathway →	+0.034	+0.081	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,427 associations by consensus.

Regulation of tumor necrosis factor-mediated signaling pathway by FAM71A expression — BLOOD_Lymphoma

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