Across TCGA patient cohorts, FAM66B mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM66B-associated genes across cancer lineages are RN7SL596P, MIR4510, and SNORD116-10. Each is linked with FAM66B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM66B-to-partner and partner-to-FAM66B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM66B→partner) and Y-score (partner→FAM66B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL596P →	+0.285	+4.326	.005	.007	3	1
UCEC	MIR4510 →	+0.529	+5.453	<.001	.002	3	1
UCEC	SNORD116-10 →	+0.553	+5.335	<.001	.003	3	1
UCEC	RNU6-1082P →	+0.446	+4.551	<.001	.009	3	1
UCEC	RNU6-1151P →	+0.521	+4.771	<.001	.006	3	1
UCEC	RNU6-1228P →	+0.413	+6.049	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

FAM66B survival (RNA) · tumor vs normal (RNA) · all FAM66B data types