FAM53C

Across TCGA patient cohorts, FAM53C RNA expression is significantly associated with the protein abundance of many other proteins, with 8,914 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM53C-associated proteins across cancer lineages are RRBP1, KDM3B, and MCM3. Each is linked with FAM53C in more than 3 cancer types. Because this analysis shows association rather than direction, both FAM53C-to-partner and partner-to-FAM53C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM53C versus RRBP1 in LSCC, with a Pearson correlation of -0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM53C→partner) and Y-score (partner→FAM53C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RRBP1 →	-0.318	-0.421	<.001	<.001	3	4
OV	KDM3B →	+0.302	+0.472	<.001	.001	3	4
LSCC	MCM3 →	+0.565	+0.356	<.001	<.001	3	4
OV	MCM4 →	+0.543	+0.462	.004	.003	3	4
LSCC	MCM5 →	+0.530	+0.361	<.001	<.001	3	4
LSCC	MCM7 →	+0.502	+0.370	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,914 associations by consensus.

FAM53C vs RRBP1 — LSCC

Explore this scatter interactively →