FAM50B

Across TCGA cell cohorts, FAM50B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,874 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FAM50B-associated GO terms across cancer lineages are Heat acclimation, Cellular heat acclimation, and Negative regulation of innate immune response. Each is linked with FAM50B in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM50B-to-partner and partner-to-FAM50B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heat acclimation grouped by FAM50B-low versus FAM50B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM50B→partner) and Y-score (partner→FAM50B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Heat acclimation →	+0.186	+1.612	.001	.003	3	8
URINARY_TRACT	Cellular heat acclimation →	+0.186	+1.612	.001	.003	3	8
KIDNEY	Negative regulation of innate immune response →	+0.129	+1.449	<.001	.001	3	7
SOFT_TISSUE	Striated muscle contraction →	+0.092	+1.695	<.001	<.001	3	7
KIDNEY	Negative regulation of response to biotic stimulus →	+0.111	+1.368	<.001	.003	3	7
BLOOD_Lymphoma	Regulation of type I interferon production →	+0.040	+1.694	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

Heat acclimation by FAM50B expression — URINARY_TRACT

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