FAM50B

Across TCGA cell cohorts, FAM50B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM50B-associated genes across cancer lineages are AVP, IAPP, and TAS2R7. Each is linked with FAM50B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM50B-to-partner and partner-to-FAM50B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by FAM50B-low versus FAM50B-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM50B→partner) and Y-score (partner→FAM50B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.031	+5.209	<.001	.005	3	1
LARGE_INTESTINE	IAPP →	+0.535	+3.906	<.001	.005	3	1
LARGE_INTESTINE	TAS2R7 →	+0.011	+4.022	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.014	+3.977	<.001	.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.006	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

AVP by FAM50B expression — BLOOD_Lymphoma

Explore this box plot interactively →