Across TCGA patient cohorts, FAM47E mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47E-associated genes across cancer lineages are RNA5SP514, IGHD5-12, and RNA5SP198. Each is linked with FAM47E in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47E-to-partner and partner-to-FAM47E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47E→partner) and Y-score (partner→FAM47E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP514 →	+1.724	+4.771	<.001	.006	3	1
UCEC	IGHD5-12 →	+1.348	+5.123	<.001	.004	3	1
UCEC	RNA5SP198 →	+1.427	+4.621	<.001	.008	3	1
UCEC	FABP5P12 →	+0.376	+5.262	<.001	.001	3	1
UCEC	RNA5SP92 →	+1.482	+4.448	<.001	.006	3	1
UCEC	RNA5SP422 →	+1.385	+4.256	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

FAM47E survival (RNA) · tumor vs normal (RNA) · all FAM47E data types