Across TCGA cell cohorts, FAM47E mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM47E-associated genes across cancer lineages are CYP2A13, HIGD1C, and CDX4. Each is linked with FAM47E in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47E-to-partner and partner-to-FAM47E results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47E→partner) and Y-score (partner→FAM47E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CYP2A13 →	+0.013	+6.569	<.001	<.001	3	1
BLOOD_Leukemia	HIGD1C →	+0.157	+5.201	<.001	.006	3	1
LARGE_INTESTINE	CDX4 →	+0.007	+3.217	.001	.006	3	1
SKIN	KIR2DS4 →	+0.013	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

FAM47E survival (RNA) · tumor vs normal (RNA) · all FAM47E data types