Across TCGA patient cohorts, FAM47C mutation is significantly associated with the RNA expression of many other genes, with 6,644 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47C-associated genes across cancer lineages are KIF18B, MIR4688, and CEP57L1. Each is linked with FAM47C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM47C-to-partner and partner-to-FAM47C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47C→partner) and Y-score (partner→FAM47C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KIF18B →	+0.707	+2.149	<.001	<.001	3	5
LGG	MIR4688 →	+0.276	+3.522	<.001	.006	3	4
SKCM	CEP57L1 →	+0.326	+1.291	<.001	.001	3	4
UCEC	KPNA5 →	+0.325	+1.266	.001	.001	3	4
UCEC	MRPL42 →	+0.357	+1.960	<.001	<.001	3	4
UCEC	LIN52 →	+0.296	+2.434	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,644 associations by consensus.

Exploration

FAM47C survival (RNA) · tumor vs normal (RNA) · all FAM47C data types