Across TCGA patient cohorts, FAM47B mutation is significantly associated with the RNA expression of many other genes, with 6,625 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47B-associated genes across cancer lineages are GMNN, TWF1, and FGD5. Each is linked with FAM47B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM47B-to-partner and partner-to-FAM47B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47B→partner) and Y-score (partner→FAM47B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GMNN →	+0.569	+2.021	<.001	<.001	3	5
UCEC	TWF1 →	+0.494	+1.893	<.001	<.001	3	4
UCEC	FGD5 →	-0.563	-1.841	<.001	<.001	3	4
UCEC	BTNL9 →	-0.721	-2.241	<.001	<.001	3	4
UCEC	CKAP2L →	+0.560	+1.296	<.001	<.001	3	4
UCEC	ARL6IP1 →	+0.431	+2.091	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,625 associations by consensus.

Exploration

FAM47B survival (RNA) · tumor vs normal (RNA) · all FAM47B data types