Across TCGA patient cohorts, FAM47B mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47B-associated genes across cancer lineages are eEF2, p38-MAPK_pT180_Y182, and PCNA. Each is linked with FAM47B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM47B-to-partner and partner-to-FAM47B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47B→partner) and Y-score (partner→FAM47B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.247	+1.765	.009	.011	3	3
UCEC	p38-MAPK_pT180_Y182 →	-0.265	-1.459	.027	.011	3	3
COAD	PCNA →	+0.286	+1.671	<.001	.006	3	3
LUAD	Akt →	-0.262	-1.736	.030	.006	3	2
LUAD	p70-S6K →	+0.175	+1.700	.013	.038	3	2
LUAD	PRDX1 →	+0.255	+1.891	.003	.027	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

FAM47B survival (RNA) · tumor vs normal (RNA) · all FAM47B data types