Across TCGA cell cohorts, FAM47B mutation is significantly associated with the mutation status of many other genes, with 4,460 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM47B-associated genes across cancer lineages are BICRA, SALL3, and YLPM1. Each is linked with FAM47B in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM47B-to-partner and partner-to-FAM47B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47B→partner) and Y-score (partner→FAM47B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	BICRA →	+2.303	+2.674	<.001	<.001	1	5
BLOOD_Leukemia	SALL3 →	+2.428	+2.766	<.001	<.001	1	5
LUNG_NSCLC_LUAD	YLPM1 →	+3.399	+3.399	<.001	<.001	1	5
BLOOD_Leukemia	BCL11B →	+2.380	+2.958	<.001	<.001	1	5
LARGE_INTESTINE	KL →	+2.614	+2.108	.001	.001	1	5
PANCREAS	FBN2 →	+3.777	+3.444	.001	.001	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,460 associations by consensus.

Exploration

FAM47B survival (RNA) · tumor vs normal (RNA) · all FAM47B data types