Across TCGA patient cohorts, FAM47A protein abundance is significantly associated with the RNA expression of many other genes, with 285 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM47A-associated genes across cancer lineages are ECM2, GRIN3B, and GPAM. Each is linked with FAM47A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47A-to-partner and partner-to-FAM47A results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47A→partner) and Y-score (partner→FAM47A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ECM2 →	-0.623	-0.769	.001	.004	3	1
LSCC	GRIN3B →	+0.945	+1.355	.002	.003	3	1
LSCC	GPAM →	-0.453	-0.770	.008	.005	3	1
LSCC	VSTM2L →	+1.276	+0.717	.009	.009	3	1
LSCC	UBE2L6 →	+1.105	+0.580	.001	.009	3	1
LSCC	ZNF404 →	-0.575	-0.723	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 285 associations by consensus.

Exploration

FAM47A survival (RNA) · tumor vs normal (RNA) · all FAM47A data types