Across TCGA patient cohorts, FAM47A mutation is significantly associated with the RNA expression of many other genes, with 6,521 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM47A-associated genes across cancer lineages are SKA1, HASPIN, and ATP1B2. Each is linked with FAM47A in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM47A-to-partner and partner-to-FAM47A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47A→partner) and Y-score (partner→FAM47A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.788	+2.395	<.001	<.001	3	5
UCEC	HASPIN →	+0.734	+1.584	<.001	<.001	3	5
UCEC	ATP1B2 →	-0.512	-2.190	.001	<.001	3	5
LUAD	CELSR3 →	+0.638	+1.784	<.001	<.001	3	5
UCEC	FEN1 →	+0.542	+2.069	<.001	<.001	3	5
UCEC	CHAF1A →	+0.634	+1.895	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,521 associations by consensus.

Exploration

FAM47A survival (RNA) · tumor vs normal (RNA) · all FAM47A data types