Across TCGA cell cohorts, FAM47A mutation is significantly associated with the RNA expression of many other genes, with 327 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM47A-associated genes across cancer lineages are F9, CHRNA4, and CCL18. Each is linked with FAM47A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM47A-to-partner and partner-to-FAM47A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM47A→partner) and Y-score (partner→FAM47A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	F9 →	+0.027	+4.643	<.001	.004	3	2
BLOOD_Leukemia	CHRNA4 →	+0.016	+3.556	.002	.001	3	2
LUNG_NSCLC_LUAD	CCL18 →	+0.019	+2.628	.001	.001	3	2
LARGE_INTESTINE	SMIM20 →	+0.623	+3.087	.005	.006	3	2
LARGE_INTESTINE	HPF1 →	+0.618	+3.137	.005	.007	3	2
SOFT_TISSUE	IFNA8 →	+0.034	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 327 associations by consensus.

Exploration

FAM47A survival (RNA) · tumor vs normal (RNA) · all FAM47A data types