Across TCGA pan-cancer cohorts, FAM43A Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FAM43A data layer compared with 25 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FAM43A Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAM43A expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

UCEC and COAD are the cancer types where FAM43A Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
COAD	DFS	Median	All	1.000	0.775	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FAM43A tumor-vs-normal RNA expression · all FAM43A data types