Across TCGA pan-cancer cohorts, FAM43A mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FAM43A data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM43A mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM43A expression acts as an unfavorable survival marker, although some lineages such as GBM and CCRCC show a favorable association.

LUAD, GBM, and CCRCC are the cancer types where FAM43A mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.851	1.000	.012	11	view →
GBM	OS	Median	All	0.582	0.351	.030	3	view →
CCRCC	OS	Median	All	1.000	0.636	.012	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: FAM43A tumor-vs-normal RNA expression · all FAM43A data types