Across TCGA patient cohorts, FAM43A mutation is significantly associated with the RNA expression of many other genes, with 180 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM43A-associated genes across cancer lineages are NPM1P1, ERI1, and TXNL4B. Each is linked with FAM43A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM43A-to-partner and partner-to-FAM43A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43A→partner) and Y-score (partner→FAM43A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NPM1P1 →	+0.317	+2.909	.006	.005	3	2
COAD	ERI1 →	+0.579	+3.598	.003	.001	3	2
COAD	TXNL4B →	+0.341	+2.509	.004	.009	3	2
COAD	CISD2 →	+0.483	+3.230	<.001	.009	3	2
COAD	WDR41 →	+0.478	+3.625	<.001	.001	3	2
COAD	AP3S1 →	+0.548	+3.332	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

Exploration

FAM43A survival (RNA) · tumor vs normal (RNA) · all FAM43A data types