Across TCGA patient cohorts, FAM43A mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FAM43A-associated genes across cancer lineages are INPP4B, JNK_pT183_Y185, and PRDX1. Each is linked with FAM43A in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM43A-to-partner and partner-to-FAM43A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43A→partner) and Y-score (partner→FAM43A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	INPP4B →	-0.396	-3.000	.031	.035	3	1
COAD	JNK_pT183_Y185 →	-0.376	-3.169	.003	.018	3	1
COAD	PRDX1 →	+0.162	+3.195	.030	.010	3	1
COAD	Caspase-7-cleavedD198 →	+1.020	+3.178	.008	.010	3	1
COAD	4E-BP1 →	+0.350	+3.178	.001	.010	1	3
COAD	TFRC →	+0.846	+3.195	.001	.010	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

FAM43A survival (RNA) · tumor vs normal (RNA) · all FAM43A data types