Across TCGA cell cohorts, FAM43A mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FAM43A-associated genes across cancer lineages are GPR26, SCGB3A2, and OR10Q1. Each is linked with FAM43A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM43A-to-partner and partner-to-FAM43A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM43A→partner) and Y-score (partner→FAM43A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GPR26 →	+0.077	+5.539	<.001	.003	3	1
BLOOD_Leukemia	SCGB3A2 →	+0.144	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR10Q1 →	+0.032	+5.969	<.001	.001	3	1
BLOOD_Leukemia	LRRC55 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	IQCM →	+0.038	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ADAM7 →	+0.035	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration

FAM43A survival (RNA) · tumor vs normal (RNA) · all FAM43A data types