FAM41C

Across TCGA patient cohorts, FAM41C RNA expression is significantly associated with the go_rna of many other GO terms, with 6,766 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM41C-associated GO terms across cancer lineages are Methylation, Obsolete histone H3-K4 methylation, and Regulation of canonical Wnt signaling pathway. Each is linked with FAM41C in more than 15 cancer types. Because this analysis shows association rather than direction, both FAM41C-to-partner and partner-to-FAM41C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Methylation grouped by FAM41C-low versus FAM41C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM41C→partner) and Y-score (partner→FAM41C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Methylation →	+0.041	+0.161	<.001	<.001	3	16
THYM	Obsolete histone H3-K4 methylation →	+0.068	+1.231	<.001	<.001	3	15
STAD	Regulation of canonical Wnt signaling pathway →	+0.065	+0.209	<.001	<.001	3	15
STAD	Obsolete histone modification →	+0.075	+0.196	<.001	<.001	3	15
STAD	Macromolecule methylation →	+0.041	+0.134	<.001	<.001	3	15
STAD	tRNA metabolic process →	+0.043	+0.141	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,766 associations by consensus.

Methylation by FAM41C expression — STAD

Explore this box plot interactively →