Across TCGA patient cohorts, FAM3C mutation is significantly associated with the RNA expression of many other genes, with 1,990 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM3C-associated genes across cancer lineages are RARRES2P6, RNA5SP421, and RPL12P34. Each is linked with FAM3C in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM3C-to-partner and partner-to-FAM3C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM3C→partner) and Y-score (partner→FAM3C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RARRES2P6 →	+0.727	+4.363	<.001	.007	3	2
UCEC	RNA5SP421 →	+0.734	+2.188	<.001	.007	3	2
LUAD	RPL12P34 →	+0.161	+5.157	<.001	.007	3	2
LUAD	LINC02353 →	+0.180	+5.044	<.001	.009	3	2
UCEC	MIR548AL →	+0.235	+3.351	<.001	.004	3	2
BRCA	MIR6885 →	+0.834	+5.070	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,990 associations by consensus.

Exploration

FAM3C survival (RNA) · tumor vs normal (RNA) · all FAM3C data types