Across TCGA pan-cancer cohorts, FAM32EP RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of FAM32EP’s most consistent transcriptional readouts.
The strongest signal is observed in bladder urothelial carcinoma (BLCA), where FAM32EP RNA is repressed in tumor relative to normal tissue. In most cancer types FAM32EP is over-expressed in tumor, although a few such as BLCA and UCEC show the opposite, repressed pattern.
BLCA and UCEC are the cancer types where FAM32EP tumor–normal differential expression is most reproducible.