Q-omics provides the consensus-scored FAM32EP profile across patient tissues and cancer cell-line models. FAM32EP expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, FAM32EP is differentially expressed in 2, with the highest sampling consensus in BLCA. Additionally, FAM32EP RNA expression shows 3,597 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, BLCA, and STAD as cancer lineages where FAM32EP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAM32EP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAM32EP survival associations across molecular data types. FAM32EP RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAM32EP RNA expression–survival associations across cancer types. High FAM32EP expression shows unfavorable associations in KICH, THCA, LIHC, SKCM, GBM and LGG. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for FAM32EP RNA expression.
This table summarizes FAM32EP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for FAM32EP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAM32EP shows lower tumor expression in BLCA and UCEC. The BLCA box plot shows higher FAM32EP RNA expression in normal versus tumor tissue (log2 FC = −0.141, t-test p = .037).
This table shows molecular features associated with FAM32EP in patient tissues and cancer cell lines. In patient samples, FAM32EP shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
