FAM30C

Across TCGA patient cohorts, FAM30C RNA expression is significantly associated with the go_rna of many other GO terms, with 3,995 significant associations in total. LGG shows the largest number of these associations.

The most reproducible FAM30C-associated GO terms across cancer lineages are Positive regulation of translation, Positive regulation of receptor catabolic process, and Positive regulation of amide metabolic process. Each is linked with FAM30C in more than 4 cancer types. Because this analysis shows association rather than direction, both FAM30C-to-partner and partner-to-FAM30C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translation grouped by FAM30C-low versus FAM30C-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM30C→partner) and Y-score (partner→FAM30C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of translation →	+0.053	+0.029	.002	<.001	3	5
SARC	Positive regulation of receptor catabolic process →	+0.076	+0.089	<.001	<.001	3	4
STAD	Positive regulation of amide metabolic process →	+0.049	+0.029	.003	<.001	3	4
STAD	Protein acetylation →	+0.042	+0.023	.008	.005	3	4
STAD	Endosome to lysosome transport →	+0.042	+0.025	.009	.002	3	4
STAD	RNA modification →	+0.042	+0.024	.006	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

Positive regulation of translation by FAM30C expression — STAD

Explore this box plot interactively →