FAM30C

Across TCGA pan-cancer cohorts, FAM30C RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated FAM30C data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher FAM30C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM30C expression acts as an unfavorable survival marker, although some lineages such as LGG and LIHC show a favorable association.

TGCT, COAD, and LGG are the cancer types where FAM30C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
TGCT	OS	Tertile	All	0.734	0.976	<.001	72	view →
COAD	OS	Tertile	All	0.153	0.674	.004	48	view →
LGG	OS	Tertile	All	0.904	0.754	.003	19	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
KIRP	DFS	Tertile	III,IV	0.038	0.723	<.001	18	view →
UVM	OS	Tertile	All	0.292	0.674	.035	18	view →
LIHC	DFS	Tertile	III,IV	1.000	0.293	.030	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

FAM30C–TGCT (OS)

Open the TGCT breakdown →