FAM27E3

Across TCGA patient cohorts, FAM27E3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,367 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FAM27E3-associated proteins across cancer lineages are SNW1, BRD3, and SUPT16H. Each is linked with FAM27E3 in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM27E3-to-partner and partner-to-FAM27E3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM27E3 versus SNW1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM27E3→partner) and Y-score (partner→FAM27E3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNW1 →	+0.276	+0.535	<.001	<.001	3	6
GBM	BRD3 →	+0.328	+0.460	<.001	<.001	3	6
LSCC	SUPT16H →	+0.463	+0.537	<.001	<.001	3	6
GBM	ZFR →	+0.212	+0.379	<.001	<.001	3	5
BRCA	MYBBP1A →	+0.436	+0.489	<.001	<.001	3	5
HNSC	ZNF326 →	+0.396	+0.678	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,367 associations by consensus.

FAM27E3 vs SNW1 — GBM

Explore this scatter interactively →