Across TCGA patient cohorts, FAM25E RNA expression is significantly associated with the go_rna of many other GO terms, with 6,696 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM25E-associated GO terms across cancer lineages are Regulation of telomere maintenance in response to DNA damage, Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5', and Mitochondrial gene expression. Each is linked with FAM25E in more than 16 cancer types. Because this analysis shows association rather than direction, both FAM25E-to-partner and partner-to-FAM25E results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25E→partner) and Y-score (partner→FAM25E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of telomere maintenance in response to DNA damage →	+0.048	+0.131	<.001	<.001	3	17
STAD	Obsolete nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5' →	+0.040	+0.109	<.001	<.001	3	15
STAD	Mitochondrial gene expression →	+0.061	+0.134	<.001	<.001	3	14
STAD	Protein methylation →	+0.050	+0.120	<.001	<.001	3	14
STAD	Protein targeting to mitochondrion →	+0.054	+0.115	<.001	<.001	3	14
KIRC	Depyrimidination →	+0.042	+0.100	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,696 associations by consensus.

Exploration

FAM25E survival (RNA) · tumor vs normal (RNA) · all FAM25E data types