FAM25C

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FAM25C RNA expression is significantly associated with the go_rna of many other GO terms, with 937 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FAM25C-associated GO terms across cancer lineages are Mitochondrion to lysosome vesicle-mediated transport, Mitochondrion-derived vesicle mediated transport, and Cellular response to platelet-derived growth factor stimulus. Each is linked with FAM25C in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM25C-to-partner and partner-to-FAM25C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrion to lysosome vesicle-mediated transport grouped by FAM25C-low versus FAM25C-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25C→partner) and Y-score (partner→FAM25C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHMitochondrion to lysosome vesicle-mediated transport →+0.205+0.457<.001.00235
STOMACHMitochondrion-derived vesicle mediated transport →+0.205+0.457<.001.00235
PANCREASCellular response to platelet-derived growth factor stimulus →+0.077+0.606.002.00735
OVARYRibonucleoside biosynthetic process →+0.125+0.451.002.00726
OESOPHAGUSSkin development →+0.107+1.361.006.00135
LARGE_INTESTINENon-canonical NF-kappaB signal transduction →+0.054+0.314<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 937 associations by consensus.

Mitochondrion to lysosome vesicle-mediated transport by FAM25C expression — STOMACH

Box plot of Mitochondrion to lysosome vesicle-mediated transport in FAM25C-low vs FAM25C-high samples in STOMACH.

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Exploration