Across TCGA patient cohorts, FAM25A mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM25A-associated genes across cancer lineages are SPATA19, RPL23AP88, and MIR6780A. Each is linked with FAM25A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM25A-to-partner and partner-to-FAM25A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM25A→partner) and Y-score (partner→FAM25A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPATA19 →	+0.135	+4.206	<.001	.001	3	1
UCEC	RPL23AP88 →	+0.233	+3.169	.004	.006	3	1
UCEC	MIR6780A →	+0.555	+3.386	<.001	.008	3	1
UCEC	IL31 →	+0.501	+3.774	<.001	.003	3	1
UCEC	MIR200C →	+0.931	+3.658	<.001	.008	3	1
UCEC	IGHD6-6 →	+1.410	+4.005	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

FAM25A survival (RNA) · tumor vs normal (RNA) · all FAM25A data types