FAM247B

Across TCGA pan-cancer cohorts, FAM247B RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated FAM247B data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM247B RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated FAM247B expression acts as an unfavorable survival marker, although some lineages such as LUAD and BRCA show a favorable association.

LUAD, ACC, and BRCA are the cancer types where FAM247B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	II,III,IV	0.702	0.406	<.001	65	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	63	view →
BRCA	OS	Tertile	III,IV	0.834	0.455	.005	51	view →
LIHC	OS	Tertile	II,III,IV	0.207	0.479	.001	51	view →
COAD	DFS	Tertile	All	0.410	0.719	.001	33	view →
KIRP	DFS	Tertile	IV	1.000	0.139	.018	22	view →
THCA	DFS	Tertile	All	0.959	0.913	.008	20	view →
CESC	OS	Tertile	III,IV	0.167	0.657	.044	18	view →
KIRC	DFS	Tertile	III,IV	0.620	0.780	.006	14	view →
UCS	DFS	Quartile	II,III,IV	0.567	0.156	.026	12	view →
TGCT	DFS	Quartile	All	0.668	0.886	.014	10	view →
READ	OS	Tertile	III,IV	0.287	0.772	.030	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

FAM247B–LUAD (DFS)

Open the LUAD breakdown →