FAM242A

Across TCGA pan-cancer cohorts, FAM242A RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated FAM242A data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FAM242A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FAM242A expression acts as an unfavorable survival marker, although some lineages such as LGG and GBM show a favorable association.

MESO, COAD, and ACC are the cancer types where FAM242A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Tertile	II,III,IV	0.256	0.598	<.001	108	view →
COAD	DFS	Tertile	III,IV	0.168	0.710	<.001	81	view →
ACC	OS	Tertile	III,IV	0.261	0.772	<.001	51	view →
DLBC	OS	Tertile	All	0.395	0.878	.001	45	view →
LIHC	OS	Tertile	III,IV	0.139	0.634	<.001	42	view →
LGG	DFS	Median	All	0.479	0.309	<.001	36	view →
READ	OS	Tertile	III,IV	0.364	0.769	<.001	27	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
PCPG	OS	Tertile	All	0.331	0.981	.003	18	view →
UCEC	DFS	Tertile	All	0.505	0.671	.003	18	view →
SKCM	OS	Tertile	IV	0.167	0.657	.003	9	view →
PAAD	OS	Tertile	II,III,IV	0.345	0.571	.045	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

FAM242A–MESO (OS)

Open the MESO breakdown →