Across TCGA pan-cancer cohorts, FAM239B RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated FAM239B data layer.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher FAM239B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FAM239B expression acts as an unfavorable survival marker, although some lineages such as ESCA and OV show a favorable association.
LUAD, DLBC, and KIRP are the cancer types where FAM239B RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.