FAM239A

Across TCGA patient cohorts, FAM239A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,259 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible FAM239A-associated GO terms across cancer lineages are Epigenetic programming in the zygotic pronuclei, P-body assembly, and Heterochromatin organization. Each is linked with FAM239A in more than 18 cancer types. Because this analysis shows association rather than direction, both FAM239A-to-partner and partner-to-FAM239A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic programming in the zygotic pronuclei grouped by FAM239A-low versus FAM239A-high in GBM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM239A→partner) and Y-score (partner→FAM239A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	Epigenetic programming in the zygotic pronuclei →	+0.047	+0.284	<.001	<.001	2	19
DLBC	P-body assembly →	+0.053	+0.534	.001	<.001	3	16
DLBC	Heterochromatin organization →	+0.055	+0.561	.001	<.001	3	15
DLBC	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.079	+0.609	<.001	<.001	3	15
SARC	Protein desumoylation →	+0.039	+0.525	<.001	<.001	3	15
UVM	Microtubule anchoring →	+0.034	+1.274	.006	.003	1	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,259 associations by consensus.

Epigenetic programming in the zygotic pronuclei by FAM239A expression — GBM

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