FAM239A

Across TCGA patient cohorts, FAM239A mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM239A-associated genes across cancer lineages are RNU6-238P, SNORD116-24, and TRAV25. Each is linked with FAM239A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM239A-to-partner and partner-to-FAM239A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-238P grouped by FAM239A-low versus FAM239A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM239A→partner) and Y-score (partner→FAM239A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-238P →	+0.547	+3.134	.002	.005	3	1
UCEC	SNORD116-24 →	+0.971	+3.833	.003	.003	3	1
UCEC	TRAV25 →	+0.526	+3.606	.002	.006	3	1
UCEC	IGHD1-26 →	+0.966	+3.747	<.001	.003	3	1
UCEC	IGHD3-22 →	+2.077	+3.051	.005	.005	3	1
UCEC	IGHD6-19 →	+0.695	+3.683	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

RNU6-238P by FAM239A expression — UCEC

Explore this box plot interactively →