FAM238A

Across TCGA patient cohorts, FAM238A mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM238A-associated genes across cancer lineages are RN7SKP133, RNU6-1138P, and RNA5SP86. Each is linked with FAM238A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM238A-to-partner and partner-to-FAM238A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP133 grouped by FAM238A-low versus FAM238A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM238A→partner) and Y-score (partner→FAM238A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SKP133 →	+0.493	+5.937	.005	.002	3	1
UCEC	RNU6-1138P →	+0.705	+5.081	<.001	.008	3	1
UCEC	RNA5SP86 →	+2.150	+5.299	<.001	.006	3	1
UCEC	RNU6-482P →	+0.899	+5.031	<.001	.009	3	1
UCEC	RPL5P19 →	+0.195	+5.694	<.001	.003	3	1
UCEC	RNU6ATAC31P →	+0.482	+5.081	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RN7SKP133 by FAM238A expression — UCEC

Explore this box plot interactively →