Across TCGA patient cohorts, FAM236D RNA expression is significantly associated with the go_rna of many other GO terms, with 5,871 significant associations in total. STAD shows the largest number of these associations.

The most reproducible FAM236D-associated GO terms across cancer lineages are Positive regulation of sterol transport, Endocytic recycling, and Negative regulation of neuron differentiation. Each is linked with FAM236D in more than 7 cancer types. Because this analysis shows association rather than direction, both FAM236D-to-partner and partner-to-FAM236D results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM236D→partner) and Y-score (partner→FAM236D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of sterol transport →	+0.106	+0.027	<.001	.004	3	7
STAD	Endocytic recycling →	+0.147	+0.042	<.001	<.001	3	7
ESCA	Negative regulation of neuron differentiation →	+0.151	+0.044	<.001	.004	3	7
STAD	Regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator →	+0.147	+0.019	<.001	.001	3	6
STAD	Positive regulation of myoblast differentiation →	+0.120	+0.041	<.001	<.001	3	6
STAD	Schwann cell differentiation →	+0.131	+0.020	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,871 associations by consensus.

Exploration

FAM236D survival (RNA) · tumor vs normal (RNA) · all FAM236D data types