Across TCGA pan-cancer cohorts, FAM236D RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of FAM236D’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where FAM236D RNA is repressed in tumor relative to normal tissue. In most cancer types FAM236D is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

BRCA are the cancer types where FAM236D tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FAM236D RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	II,III,IV	−0.115	<.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: FAM236D RNA expression & survival · all FAM236D data types